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Our Mission

Research in the Alabi lab seeks to understand how the composition and sequence of a macromolecular chain affects its chemical, structural and biological properties with an eye towards engineering sustainable materials and biomolecular therapeutics. We are a diverse group with interest in the assembly of new sequence-defined macromolecules that can be used to create stimuli-responsive materials, develop efficient drug delivery bioconjugates and design potent antimicrobial agents.

Featured News

Rising Stars in Drug Delivery Webinar

August 27, 2020

NSF Awarded C-GEM Phase-II Funding.

August 27, 2020

This five-year $20 million grant will fund C-GEM research in 14 laboratories at UC Berkeley, Yale, Stanford, Cornell, Boston College, and St. Jude Children’s Research Hospital. We are really excited to be part of this amazing team. Looking forward to the next 5 years o...

Decomplexation as a rate limitation in the thiol-Michael addition of N-acrylamides

August 27, 2020

Organic and Biomolecular Chemistry, 2020

Joseph S. Brown, Andrew W. Ruttinger, Akash J. Vaidya, Christopher A. Alabi and Paulette Clancy DOI: 10.1039/D0OB00726A

Congrats to our recent graduate, Dr. Christine Artim! Best of luck at Pall Scientific

June 3, 2020

Thiol-Ene Networks from Sequence-Defined Polyurethane Macromers

March 30, 2020

J. Am. Chem. Soc., 2020

Emily A. Hoff, Guilhem X. De Hoe, Christopher M. Mulvaney, Marc A. Hilmyer, and Christopher A. Alabi

DOI: 10.1021/jacs.0c00759

Design of protein-based “turn on” molecular probes for intracellular bond cleavage

December 10, 2019

Mol. Syst. Des. Eng., 2019

Michelle R. Sorkin, Joshua A. Walker, Francis Ledesma, Nicole Torosian, and Christopher A. Alabi

DOI: 10.1039/C9ME00147F

Hydrophilic Sequence-Defined Cross-Linkers for Antibody–Drug Conjugates

November 12, 2019

Bioconjugate Chemistry. 2019

Joshua A. Walker, Michelle R. Sorkin, Francis Ledesma, Sneha R. Kabaria, Robyn M. Barfield, David Rabuka and Christopher A. Alabi

DOI: 10.1021/acs.bioconjchem.9b00713

Halloween 2019: antALABI's

November 6, 2019

The picture says it all!

Fleming Molecular Engineering Laboratory

November 6, 2019

Many thanks to the Fleming's for their generous donation towards our newly built laboratory!

Responsive Antibody Conjugates Enable Quantitative Determination of Intracellular Bond Degradation Rate

October 16, 2019

Cell Chemical Biology. 2019

Michelle R. Sorkin, Joshua A. Walker, Sneha R. Kabaria, Nicole P. Torosian and Christopher A. Alabi

DOI: 10.1016/j.chembiol.2019.09.008

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